What Is Biological Age and How Do You Calculate It?

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Determining biological age is based on several factors, including your genetics and your current health status. You can obtain epigenetic data from your blood or some other source. For example, DNA methylation, a chemical modification to DNA, regulates which genes are turned on or off. There are specific areas of the genome with increased or decreased methylation as we age. This information can help you to learn how to calculate your biological age, understand your biological age, and what you need to do to reverse the aging process at a biological level.


Recently, the scientific community has been looking for biomarkers that can be used for objectively determining a person’s biological age. The epigenetic clock, glycan clock, and methylation clock have all been found to correlate with biological age. Increased biological age is correlated with the likelihood of developing certain diseases later in life. Moreover, these clocks can also be used to determine morbidity and mortality, thereby helping determine the genetic risk factors.

In addition to the Framingham Risk Score, several other approaches have been suggested to calculate biological age. One such attempt was the development of a multisystem dysregulation score aimed at predicting the occurrence of multiple health outcomes at an older age. Multisystem dysregulation (allostatic load) predicted multiple health outcomes in older age. Advances in geroscience and a desire to interfere in the aging process prompted the creation of such methods.

Methods of calculating your biological age

There are several methods of calculating your biological age. The most accurate method is epigenetic clocks, and doctors can calculate your age by analyzing specific blood factors, like the length of telomeres. Blood markers can also estimate your age, but these methods are less accurate than epigenetic clocks. While epigenetic clocks are the most accurate, other methods may be more accurate. Here are some other methods you might want to try.

Blood-based methods: Thorne’s Biological Age method uses blood biomarkers to estimate your biological age. The tests look at different factors in your blood, including cholesterol, hemoglobin, and markers of inflammation and glucose resistance. Clinical measurements, such as blood pressure and heart rate, may also be used to estimate your biological age. The good news is that the results of these tests are clinically useful and consistent across the population.

Reversing the aging process at a biological level

Scientists at the Salk Institute for Biological Studies have found a way to reverse cell aging processes. As a result, they were able to extend the life span of adult mice and promote their recovery from injury. Moreover, this method could revert the aging process in mice that had already developed lethal tumors. The next step is to test whether the technique would work in humans. But in the meantime, the researchers are hopeful.

The reprogramming method has proven to be extremely successful in experiments with single cells and whole organisms. Unlike humans, jellyfish and other small organisms can maintain a seemingly indefinite lifespan. Scientists hope to one-day use reprogramming as a therapeutic approach to reverse the aging process in humans. The research could also lead to new, more radical treatments. If successful, the reprogramming method could help humans achieve similar longevity.

Future uses of biological age.

The future of biological age may be a big one. It could be a tool for evaluating overall placement on the healthy aging trajectory and measuring susceptibility to disease. Developing a reliable biological age metric could have profound implications in the health care industry and beyond. 

The development of validated biomarkers to estimate a person’s biological age is a major milestone in the field of aging. These markers can help us anticipate our lifespan and health span and predict how long we will live and how frail we’ll be in the late stages of life. There is a growing body of scientific literature on biomarkers to assess the aging process. By understanding the role of aging in human health, we can determine the best treatment to address a disease or improve quality of life.

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